A Genetic Basis for Functional Hypothalamic Amenorrhea

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A genetic basis for functional hypothalamic amenorrhea.

BACKGROUND Functional hypothalamic amenorrhea is a reversible form of gonadotropin-releasing hormone (GnRH) deficiency commonly triggered by stressors such as excessive exercise, nutritional deficits, or psychological distress. Women vary in their susceptibility to inhibition of the reproductive axis by such stressors, but it is unknown whether this variability reflects a genetic predisposition...

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Functional Hypothalamic Amenorrhea

Copyright © 2010 Massachusetts Medical Society. A 16-year-old girl presents for evaluation of secondary amenorrhea. Her menarche was at the age of 12 years. Since she started running for exercise and sport at the age of 14 years, her menstrual periods have become lighter and less frequent. Her last menstrual period was 6 months ago. She has lost 2.3 kg (5 lb) over the past 3 months and reports ...

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Treatment of functional hypothalamic amenorrhea with hypnotherapy.

OBJECTIVE To determine the effects of hypnotherapy on resumption of menstruation in patients with functional hypothalamic amenorrhea (FHA). DESIGN Uncontrolled clinical study. SETTING Academic clinical care center. PATIENT(S) Twelve consecutive women with FHA were selected. INTERVENTION(S) A single 45- to 70-minute session of hypnotherapy was administered, and patients were observed for...

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Functional Hypothalamic Amenorrhea: An Endocrine Society Clinical Practice Guideline.

Cosponsoring Associations The American Society for Reproductive Medicine, the European Society of Endocrinology, and the Pediatric Endocrine Society. This guideline was funded by the Endocrine Society. Objective To formulate clinical practice guidelines for the diagnosis and treatment of functional hypothalamic amenorrhea (FHA). Participants The participants include an Endocrine Society-app...

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Functional hypothalamic amenorrhea and its influence on women’s health

INTRODUCTION Functional hypothalamic amenorrhea (FHA) is one of the most common causes of secondary amenorrhea. There are three types of FHA: weight loss-related, stress-related, and exercise-related amenorrhea. FHA results from the aberrations in pulsatile gonadotropin-releasing hormone (GnRH) secretion, which in turn causes impairment of the gonadotropins (follicle-stimulating hormone and lut...

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ژورنال

عنوان ژورنال: Obstetrical & Gynecological Survey

سال: 2011

ISSN: 0029-7828

DOI: 10.1097/ogx.0b013e31822f94c4